Meso Fat, or targeted fat-dissolving injections, has become an increasingly popular cosmetic procedure in Thailand, especially among those looking to refine facial contours, reduce cheeks and double chin, or reshape body proportions without surgery. Its main advantage lies in using fine needles to inject agents that break down fat cells, allowing the body to naturally eliminate them.
This article covers everything you need to know about Meso Fat—from what it is, how it works, benefits and drawbacks, pricing, and expected results, to precautions and frequently asked questions—so you can make an informed decision based on accurate and safe information.
Meso Fat, or Mesotherapy Fat Reduction, is a non-surgical fat reduction technique that involves injecting lipolytic agents directly into targeted areas of subcutaneous fat, such as the cheeks, double chin, or upper arms. The procedure uses fine needles to deliver the substances into the fat layer beneath the skin.
The active compounds commonly used in Meso Fat include Phosphatidylcholine (PPC) and Deoxycholic Acid (DCA). Medical studies have shown that these agents can break down the cell membranes of adipocytes (fat cells), releasing the fat content, which is then metabolized and eliminated from the body via natural processes such as lipolysis and lymphatic drainage.
According to the American Society for Dermatologic Surgery (ASDS) and the Thai Food and Drug Administration (FDA), Deoxycholic Acid has been approved for submental fat reduction in certain products, such as Kybella® (FDA, 2015). PPC, while widely used in Asia and Europe, may not be officially approved for all indications in some countries, but research supports its effectiveness when administered at the proper dosage and with the correct technique.
Therefore, Meso Fat offers a targeted fat reduction solution for stubborn fat deposits that do not respond to diet or exercise. However, the procedure should be performed by an experienced medical professional, as the choice of agent, dosage, and injection technique all influence both the effectiveness and safety of the treatment.
Meso Fat injections in the cheek and double chin areas work directly on the localized fat deposits within the subcutaneous fat layer of the face and under the chin. These areas are prone to storing fat that can be difficult to eliminate through diet or exercise alone.
The main agents, such as Phosphatidylcholine (PPC) and Deoxycholic Acid (DCA), disrupt the membranes of fat cells (cell membrane lysis), releasing the stored fat. The body then removes this fat through the lymphatic system and natural metabolic processes. Over time, this leads to a reduction in fat volume, resulting in a more defined facial contour, a smaller double chin, and an overall slimmer face appearance.
The visibility of results depends on factors such as the initial amount of fat, injection technique, dosage, and individual body response. Most patients begin to notice changes within 2–4 weeks after the procedure, with 2–4 sessions typically recommended to achieve the desired outcome.
According to the American Board of Cosmetic Surgery (ABCS), Meso Fat is an effective option for reducing mild to moderate cheek and submental fat without surgery. However, it should be performed by an experienced medical professional to minimize side effects such as swelling, bruising, or inflammation.
While Meso Fat is most commonly used for reducing fat in the cheeks and double chin, the same technique can also be applied to other areas of the body. The principle remains the same—injecting lipolytic agents such as Phosphatidylcholine (PPC) and Deoxycholic Acid (DCA) into the subcutaneous fat layer of the targeted area to break down fat cells.
Common treatment areas include:
However, the size of the treatment area and the amount of fat will affect both the dosage and the number of sessions required. Larger areas, such as the abdomen, typically require more product and multiple treatments for optimal results.
According to the International Association for Physicians in Aesthetic Medicine (IAPAM), using Meso Fat for body contouring should only be done under medical supervision, with careful dosage planning to minimize risks such as significant swelling or the formation of firm nodules under the skin.
Meso Fat is ideal for individuals seeking non-surgical spot fat reduction in areas where stubborn fat remains despite diet and exercise. However, it is not suitable for everyone, and a proper medical evaluation is essential to ensure both safety and effectiveness.
Candidates who are generally suitable for Meso Fat include:
Meso Fat is not recommended for:
According to the American Academy of Cosmetic Surgery (AACS), proper candidate selection significantly reduces risks and increases the likelihood of achieving satisfactory results.
Proper preparation before undergoing Meso Fat is crucial for ensuring a smooth procedure, minimizing side effects, and achieving the desired results.
According to the American Society for Aesthetic Plastic Surgery (ASAPS), following the correct procedure and post-care instructions significantly improves safety and consistency of results with Meso Fat.
The level of discomfort experienced during Meso Fat varies from person to person, depending on skin nerve sensitivity, the injection area, and the physician’s technique. Most patients describe the sensation as a “mild sting or slight burning” when the solution enters the fat layer.
To minimize discomfort, physicians commonly use the following techniques:
Post-procedure, mild tightness or burning in the treated area may occur, typically resolving within 1–3 days. Temporary swelling and minor bruising are common and usually subside gradually.
According to the American Society for Dermatologic Surgery (ASDS), discomfort from Meso Fat is generally rated mild to moderate and is tolerable without the need for injectable anesthesia or sedation.
The number of Meso Fat sessions required for visible results depends on the initial fat volume, the treated area, and the body’s response to the treatment. While a single session may produce slight changes, multiple sessions are typically recommended for noticeable and lasting results.
General clinical guidelines for aesthetic practice:
The need for multiple treatments arises because Meso Fat works gradually. The body eliminates the broken-down fat through the lymphatic system and metabolism, rather than removing it instantly like liposuction.
According to the American Board of Cosmetic Surgery (ABCS), most patients begin to notice visible changes after the 2nd or 3rd session, with optimal results achieved after completing the full course recommended by their physician.
After a Meso Fat treatment, the body gradually eliminates the destroyed fat cells through the lymphatic system and natural metabolism. This is a progressive process, meaning visible changes are not immediate.
According to the American Society for Aesthetic Plastic Surgery (ASAPS), results from Meso Fat can last several months to over a year, provided that healthy habits and stable body weight are maintained.
Results from Meso Fat can last from several months to over a year, depending on various factors such as diet, exercise habits, and changes in body weight.
According to the American Board of Cosmetic Surgery (ABCS), patients who maintain stable body weight after Meso Fat tend to enjoy longer-lasting results and higher satisfaction rates.
Meso Fat offers unique benefits and limitations that should be considered before deciding on the treatment, ensuring it aligns with your goals and physical condition.
| Pros | Cons |
|---|---|
| Non-surgical with quick recovery | Requires multiple sessions for visible results |
| Targets localized fat areas such as cheeks and double chin | Results vary depending on individual body response |
| No downtime—return to normal activities immediately | Possible temporary swelling, redness, or bruising |
| Suitable for mild to moderate fat deposits | Not ideal for large fat deposits or significant skin laxity |
| Lower cost per session compared to liposuction | Results are temporary without weight maintenance |
According to the American Academy of Cosmetic Surgery (AACS), selecting the right fat reduction method should be a joint decision with your physician, considering your goals, desired results, and overall health.
Choosing between Meso Fat and liposuction depends on factors such as the amount of fat, desired results, health condition, and budget. Both methods have distinct advantages and limitations.
| Criteria | Meso Fat | Liposuction |
|---|---|---|
| Method | Injection of fat-dissolving agents into targeted areas | Surgical removal of fat using suction techniques |
| Recovery | Minimal downtime | 1–2 weeks of recovery time |
| Amount of fat removed | Small to moderate | Large amounts in a single session |
| Pain level | Mild to moderate discomfort | Moderate to significant pain (requires anesthesia) |
| Risks | Temporary swelling, redness, bruising | Risk of infection, bleeding, or uneven skin texture |
| Cost | Lower per session but multiple sessions required | Higher cost per procedure but results in one session |
| Best for | Individuals seeking minor contouring | Individuals with significant fat deposits wanting immediate results |
According to the American Society of Plastic Surgeons (ASPS), Meso Fat may be preferable for those wanting subtle changes without surgery, while liposuction is more suitable for large-volume fat removal with immediate results.
Meso Fat can be safely combined with regular exercise and a healthy diet, and this approach is recommended to maximize results and extend their longevity.
According to the International Journal of Obesity (2022), combining dietary control with exercise after fat reduction treatments can prolong results by 30–40% compared to making no lifestyle changes.
Following your physician’s post-care instructions after Meso Fat is essential for achieving optimal results and minimizing side effects. Avoiding certain activities in the initial recovery period plays a key role.
According to the American Society for Dermatologic Surgery (ASDS), proper post-treatment care after Meso Fat directly influences swelling reduction and ensures the injected solution works effectively.
While Meso Fat is a non-surgical procedure with minimal downtime, it still carries potential risks and side effects that patients should be aware of before undergoing treatment.
According to the American Board of Cosmetic Surgery (ABCS), risk reduction can be achieved by choosing an experienced physician, using FDA-approved or medically certified products, and strictly following post-treatment care instructions.
These prices are average estimates. A consultation is recommended to determine the appropriate number of sessions and total cost based on the individual’s fat volume and desired outcome.
Q: Does Meso Fat hurt?
A: Most people experience mild to moderate discomfort during injection. Topical anesthetic or ice is often used to reduce pain.
Q: How many sessions are needed for noticeable results?
A: Typically 2–4 sessions, depending on the amount of fat and individual body response.
Q: Is there any downtime after Meso Fat?
A: No downtime is required. Normal activities can be resumed immediately, but avoid intense exercise for the first 1–2 days.
Q: How long do the results last?
A: Between 6 months and over a year, especially if combined with regular exercise and weight management.
Q: Is Meso Fat safe?
A: Yes, when performed by an experienced physician using products approved by relevant health authorities such as the FDA.
Meso Fat is a suitable option for individuals seeking to reduce small to moderate localized fat deposits without undergoing surgery. While it does not provide permanent results, its effects can last a long time when combined with proper diet and regular exercise.
However, it is essential to undergo the procedure under the supervision of a qualified physician, use only approved products, and strictly follow post-treatment instructions to ensure both safety and optimal results.
