What Causes Melasma? Best Melasma Treatments 2025

Melasma is one of the most common skin concerns, especially among working-age individuals and those frequently exposed to sunlight. Although the brown or grayish patches on the face do not cause pain or itching, they can significantly affect confidence and appearance. Many people wonder: What causes melasma? and Which treatments actually work?

This article provides a comprehensive guide to melasma—covering its causes, types, common triggers, treatment options including creams, lasers, and modern procedures, as well as aftercare and estimated costs—helping you make informed decisions about the most suitable treatment for your skin.

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What Is Melasma?

Melasma is a skin condition caused by the overproduction of melanin, resulting in brown to dark brown patches on the skin. It most commonly appears on the face, especially the cheeks, forehead, upper lip, and nose.

Characteristics of Melasma

  • Appears as light brown, grayish, or dark brown patches
  • Usually symmetrical, affecting both sides of the face
  • More common in women than in men
  • Does not cause pain or itching but often affects self-confidence

Melasma vs. Freckles vs. Dark Spots: What’s the Difference?

Although often confused, melasma, freckles, and dark spots have distinct features and causes.

Skin Concern Characteristics Main Causes Common Locations
Melasma Brown or grayish-brown patches, usually symmetrical Sun exposure, hormones, genetics Cheeks, forehead, upper lip
Freckles Small light to dark brown spots, more visible in sunlight Genetics, UV exposure Face, shoulders, arms
Dark Spots Dark marks left after inflammation, such as acne scars Inflammation, wounds, sun damage Face and body

Types of Melasma: Epidermal, Dermal, and Mixed

Epidermal Melasma

Occurs in the epidermis (outer skin layer). Appears as dark brown patches with clear borders. This type generally responds better to treatment compared to deeper melasma.

Dermal Melasma

Located in the dermis (deeper skin layer). Appears grayish-brown or bluish-gray with blurred edges. It is more difficult to treat and usually requires medical procedures.

Mixed Melasma

The most common type, combining both epidermal and dermal features. It requires a combination of treatments to achieve noticeable improvement.

What Causes Melasma? Common Triggers

Sun Exposure

Ultraviolet (UVA/UVB) rays are the primary trigger that overstimulate melanin production, making melasma appear darker and more prominent.

Hormonal Changes

Hormonal fluctuations during pregnancy, oral contraceptive use, or hormonal imbalance can stimulate excessive pigment formation.

Genetics

Individuals with a family history of melasma are at a higher risk of developing the condition.

Inflammation and Environmental Factors

Pollution, stress, lack of sleep, and skin inflammation (such as acne) may worsen melasma visibility.

Why Is Melasma Difficult to Treat and Likely to Recur?

Multiple Contributing Factors

Melasma is influenced by a combination of sun exposure, hormones, genetics, and environmental factors, making it challenging to control.

Pigment Located Deep in the Skin

In types like dermal melasma, pigment is deposited in deeper skin layers, which topical creams and basic treatments cannot effectively reach.

Sensitive Pigment Cells

Even after treatment, pigment-producing cells can be easily reactivated by sunlight or hormonal changes, leading to recurrence.

Need for Long-Term Care

Melasma is a chronic condition. Consistent treatment and prevention strategies—such as daily sunscreen and proper skincare—are essential to maintain results.

Nutrition and Diet That May Help Reduce Melasma Risk

Antioxidant-Rich Foods

Fruits and vegetables rich in vitamin C, vitamin E, and polyphenols-such as citrus fruits, berries, and leafy greens—help reduce UV-induced collagen damage and excess pigmentation.

Healthy Fats

Sources like salmon, avocado, and nuts support skin barrier function, reduce inflammation, and promote skin repair.

Stay Hydrated

Drinking 1.5–2 liters of water daily helps maintain skin hydration and supports natural healing.

Foods and Habits to Avoid

High-sugar foods, excessive alcohol, and smoking may trigger inflammation and increase skin sensitivity to sunlight.

Can Men Get Melasma?

Prevalence in Men

Although melasma is more common in women, men can also develop it. Studies report that around 10–25% of melasma patients are male.

Triggers in Men

The causes are similar to women—mainly sun exposure and genetics. However, in men, outdoor occupations, sports activities, and lack of consistent sunscreen use are significant contributors.

Treatment for Men

Treatment approaches are similar to those for women, including depigmenting creams, laser therapy, and medical procedures. Consistent sun protection and skincare remain key to managing melasma in men.

Melasma Treatments in 2025: What Are the Options?

Topical Creams and Skincare

Depigmenting agents such as hydroquinone, vitamin C, arbutin, and niacinamide can help lighten melasma when used consistently.

Laser and Energy-Based Devices

Laser and radiofrequency technologies like Sylfirm X Plus target abnormal pigmentation and stimulate skin rejuvenation from within.

Collagen-Stimulating Injectables

Biostimulators such as PLLA or CaHA promote collagen regeneration, improving skin quality and reducing dullness.

Complementary Approaches

Antioxidant-rich nutrition, IV drips, and strict sun protection play key roles in supporting and maintaining treatment outcomes.

Melasma Creams: Do They Really Work?

Common Active Ingredients

  • Hydroquinone: Inhibits melanin production; effective with continuous use under medical supervision
  • Vitamin C: Reduces melanin formation and brightens skin
  • Arbutin and Niacinamide: Help even out skin tone and reduce discoloration

Limitations of Topical Creams

  • Require months of consistent use before visible results
  • Risk of irritation or resistance if misused
  • Less effective for deeper melasma

Who Is It Suitable For?

Topical creams are best suited for individuals with mild or superficial melasma and are often combined with medical treatments for enhanced results.

Laser Treatment for Melasma: Sylfirm X Plus 2025

Sylfirm X Plus uses radiofrequency microneedling technology to target abnormal melanin production while simultaneously stimulating collagen regeneration and skin repair.

Key Advantages

  • Treats both superficial and deep melasma effectively
  • Improves overall skin texture and radiance
  • Minimally painful with short downtime

Ideal for patients with stubborn or chronic melasma that has not responded well to topical creams or older laser technologies, seeking safe and natural-looking results.

Biostimulators: Revitalizing Skin and Improving Chronic Melasma

Biostimulators are injectable substances, such as Poly-L-lactic acid (PLLA) or Calcium Hydroxylapatite (CaHA), that stimulate the skin’s natural collagen production to restore skin structure and quality.

Benefits for Melasma Treatment

  • Strengthen overall skin quality and resilience
  • Reduce dullness and pigmentation associated with melasma
  • Enhance effectiveness when combined with lasers or topical therapies

Best for individuals with chronic melasma, along with signs of skin aging or fine lines, who seek natural-looking and long-lasting results.

Post-Laser Care for Melasma Treatment

Avoid Direct Sun Exposure

After laser treatment, the skin becomes more sensitive to UV rays. Avoid strong sunlight and apply sunscreen with SPF 50 or higher daily.

Use Gentle Skincare

Choose moisturizers or serums that soothe and hydrate the skin. Avoid harsh acids or retinoids until the skin has recovered.

Apply Cold Compress if Redness Occurs

If warmth or redness appears, gently apply a cold compress to relieve discomfort.

Follow Physician’s Instructions

Use prescribed creams or medications exactly as directed to support healing and reduce the risk of post-inflammatory pigmentation.

Real Case Reviews of Melasma Treatment at Smooth Clinic

Chronic Melasma Case

A patient with long-standing dermal melasma underwent Sylfirm X Plus combined with topical depigmenting agents. The melasma patches gradually lightened, and the skin appeared smoother.

Superficial Melasma Case

A patient with superficial melasma on the cheeks was treated with Skin Quality alongside strict sun protection. The skin tone became more even and brighter.

Melasma with Skin Aging Case

A patient with mixed melasma and signs of skin aging received Biostimulator combined with laser treatment. Results showed firmer skin with naturally lighter melasma.

Note

Outcomes vary for each individual depending on the type of melasma and personal skin response.

Frequently Asked Questions About Melasma Treatment

Can melasma be completely cured?

Melasma is a chronic condition and cannot be permanently cured. However, it can be significantly lightened and controlled with proper treatment and prevention.

How many sessions are needed to see results?

It depends on the type and severity of melasma as well as the treatment method. Multiple sessions are usually required for visible improvement.

Is the treatment painful?

Most procedures, such as laser or biostimulators, cause only mild discomfort or warmth. Topical anesthesia can be applied to minimize pain.

Is there downtime after treatment?

Generally, there may be mild redness for 1–2 days, but patients can continue their daily activities as usual.

Is melasma treatment expensive?

Costs vary depending on the treatment type and number of sessions. Prices typically range from a few thousand to tens of thousands of THB per session.

Conclusion: How to Choose the Right Melasma Treatment for You

Assess the Type and Severity of Melasma

Identify whether the melasma is superficial, dermal, or mixed in order to plan a targeted treatment approach.

Select the Most Suitable Option

  • Superficial melasma: Often responds well to depigmenting creams and lasers
  • Deep or chronic melasma: May require advanced technologies such as Sylfirm X Plus combined with biostimulators
  • Mixed melasma: Typically managed with a combination of therapies

Consult a Specialist

There is no one-size-fits-all solution. Consulting with a qualified physician ensures a personalized treatment plan for safe and long-lasting results.

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