If you’re looking for a way to deeply rejuvenate your skin—hydrating, firming, and brightening—without surgery or altering your facial features, Profhilo is one of the most advanced treatments available today and increasingly popular in aesthetic clinics worldwide.
Profhilo is not a filler, nor is it a traditional skin booster. It’s a unique bio-remodeling treatment that uses highly concentrated, pure hyaluronic acid (HA) to stimulate collagen and elastin production naturally. It’s ideal for those who want their skin to appear firmer, healthier, and more radiant without adding volume.
In this article, we’ll walk you through everything you need to know about Profhilo—from how it works, injection techniques, benefits, and real patient results, to safety, cost, and comparisons with other treatments—so you can make an informed and confident decision.
Profhilo is a new-generation skin booster made from high-concentration Hyaluronic Acid (HA). Unlike traditional fillers that add volume or contour the face, Profhilo works by stimulating the skin’s natural production of collagen and elastin. The result is firmer, more elastic, and smoother skin—achieved naturally from within.
This innovation is called Bio-Remodeling, a technique that restructures the skin using NAHYCO® Hybrid Technology. This technology combines both high and low molecular weight HA into a stabilized complex, allowing it to spread evenly under the skin and last longer than typical skin boosters.
Profhilo is widely used in leading aesthetic clinics across Europe and Asia, particularly for individuals who want rejuvenated, glowing skin without facial contouring or invasive lifting procedures.
Profhilo is manufactured by IBSA Derma, Italy, and has received CE Mark certification in Europe.
Profhilo works through a process known as Bio-Remodeling, which refers to the natural regeneration of skin structure—not by filling, but by stimulating the skin’s internal renewal.
Once injected, Profhilo spreads evenly in the subcutaneous layer without forming lumps. This is made possible by its patented NAHYCO® Hybrid Technology, which combines both low and high molecular weight Hyaluronic Acid (HA) into a single stabilized complex.
The outcome is firmer, more elastic, and naturally radiant skin—without added volume or facial reshaping.
The BAP (Bio Aesthetic Points) technique is a standardized injection method specifically designed for Profhilo. It allows for safe, even distribution of HA across the face using just 5 injection points per side (10 total).
This technique is ideal for patients seeking natural-looking, full-face skin rejuvenation without altering facial shape.
Profhilo is ideal for individuals who want to improve overall skin quality—hydration, firmness, and glow—without reshaping their face.
Profhilo injections are generally well tolerated with minimal discomfort. The procedure involves only 5 injection points per side of the face using a fine needle, and many patients report little to no pain.
Proper preparation can reduce side effects and enhance treatment outcomes.
Profhilo is designed for medium-term rejuvenation—not a one-time fix. A structured protocol helps stimulate collagen and elastin production effectively over time.
Hydration, sun protection, and good skincare habits can prolong the visible benefits of Profhilo.
A common question is whether Profhilo can make the skin brighter. The answer is: Yes, but in terms of healthy-looking radiance—not whitening or artificial glow.
What Profhilo actually improves:
However, Profhilo does not contain bleaching agents and does not change skin color. The glow it provides comes from internal hydration and collagen support—safe and natural.
Profhilo is widely praised for its skin-rejuvenating effects, but like any treatment, it comes with both benefits and considerations.
Profhilo is considered one of the safest injectable treatments, using ultra-pure Hyaluronic Acid without BDDE. This reduces the risk of allergic reactions and long-term complications.
Still, it’s important to be aware of possible side effects—though they are generally mild and temporary.
Since Profhilo is not a volumizing filler, it does not carry the same risk of migration or vascular occlusion as some traditional fillers.
Due to its growing popularity, counterfeit Profhilo products have appeared on the market. Using authentic Profhilo is crucial to ensure safety and effective results.
Fake Profhilo may not only be ineffective—it can lead to infection, inflammation, or serious complications.
Proper preparation and post-care are key to maximizing Profhilo results and minimizing potential side effects.
While Profhilo may be priced higher than typical skin boosters, it delivers deeper skin rejuvenation, longer-lasting effects, and uses advanced HA technology—making it a smart investment for those seeking visible, natural results without facial augmentation.
Note: A standard treatment course involves 2 sessions spaced 1 month apart, requiring 2 boxes for optimal results.
For those who value deep, natural skin revitalization, Profhilo offers one of the best returns on investment in non-surgical aesthetics.
Though Profhilo falls under the skin booster category, it stands apart from typical options in terms of HA concentration, technology, injection technique, and long-term effects.
| Feature | Profhilo | Other Skin Boosters |
|---|---|---|
| HA concentration | Very high (64 mg/2 ml) | Moderate to low (15–30 mg/2 ml) |
| HA molecular structure | Hybrid (high + low molecular weight) | Mostly low molecular weight only |
| Primary function | Bio-remodeling, collagen stimulation | Superficial hydration |
| Injection technique | BAP 5-point full-face injection | Multiple microinjections |
| Duration of results | Up to 6 months | Typically 1–3 months (requires repeat) |
| Best suited for | Skin laxity, full-face revitalization | Dry skin, quick glow, short-term boost |
If you’re looking for the most effective skin booster for glow in 2025, and want to compare brands like Belotero Revive, Skinvive, Flore, or Profhilo, we’ve got you covered.
Read more: Skin Booster 2025: Belotero vs Skinvive vs Flore vs Profhilo – Which One Truly Delivers the Glow?
Although both Profhilo and fillers are made from Hyaluronic Acid (HA), their purposes and effects are entirely different.
| Feature | Profhilo | Dermal Filler |
|---|---|---|
| Primary goal | Skin quality restoration (Bio-remodeling) | Volume enhancement and facial contouring |
| Visible results | Firmer, hydrated, overall skin glow | Fills deep folds, defines chin, lips, nose |
| Texture | Fluid, spreads evenly in skin | Gel-like, structured to hold shape |
| Distribution | Even spread under skin | Stays exactly where injected |
| Look & feel | Natural “skin improvement” | May appear artificial if overdone |
| Injection technique | 5-point BAP full-face method | Targeted zones (e.g. nasolabial, chin) |
Most people who undergo Profhilo describe the results as “I just look better, but no one can tell why.” The improvement is gradual and subtle—no facial shape changes or obvious signs of treatment.
Most noticeable change: A healthy glow that’s not oily, and smoother skin texture like you’ve had a great rest.
Individual results vary depending on skin condition, age, and post-treatment care.
While the face is the most common area, Profhilo can also be injected into: Neck Hands Upper arms Décolleté (chest)
It’s best to wait at least 7 days before undergoing lasers or other aesthetic procedures to allow the product to settle fully.
Yes. Especially for men who want better skin without any noticeable changes in facial shape.
Yes, Profhilo works on skin quality, while fillers and Botox target volume loss and dynamic wrinkles, respectively.
Profhilo is highly pure and free from additives or preservatives, making it suitable for sensitive skin. Still, always consult with a physician beforehand.
Profhilo is a next-generation skin booster that stands apart from both fillers and conventional HA treatments. With its patented NAHYCO® technology and high HA concentration, it delivers natural, long-lasting skin improvement without downtime or drastic changes.
It’s especially suitable for individuals experiencing early signs of skin aging, dehydration, or loss of firmness who want to enhance their skin’s overall quality and glow—subtly and safely.
Results may vary depending on individual skin conditions. Always consult with a licensed medical professional before undergoing treatment.
