What is Radiesse Plus? The 2026 Breakthrough in Facial Lifting and Rejuvenation

If you’re seeking a non-surgical way to lift, rejuvenate, and naturally fill deep lines, Radiesse Plus may be the right answer for you. Unlike conventional fillers, Radiesse Plus is a biostimulatory filler that not only fills but also stimulates collagen production within the skin for smooth, long-lasting results.

In this article, we’ll delve into what Radiesse Plus is, how it works, its ingredients, benefits, and how it differs from traditional fillers—empowering you to make an informed decision.

What is Radiesse Plus?

Radiesse Plus is a specialized filler designed not just to fill deep facial lines but also to stimulate the natural production of collagen in the skin. It is ideal for individuals seeking longer-lasting results than typical fillers and features added comfort during injection due to its lidocaine content—an anesthetic commonly used in dental procedures.

The main component of Radiesse Plus is Calcium Hydroxylapatite (CaHA), a biocompatible substance that is naturally broken down by the body. These CaHA particles stimulate collagen production, resulting in firmer, more elastic skin with improved structure, even after the filler has been metabolized.

How is Radiesse Plus Different From Regular Fillers?

• Long-lasting results: 12–24 months without frequent top-ups
• Deep skin rejuvenation, not just superficial filling
• Natural-looking results that improve gradually over time
• Contains Lidocaine for reduced discomfort—no need for separate numbing

Common Treatment Areas

• Nasolabial folds, chin, temples
• Jawline and neck lifting
• Skin rejuvenation on hands, arms, and other thin-skinned areas

Radiesse Plus vs Radiesse

Many may recognize the name “Radiesse” and wonder about the difference. Both use CaHA as the core ingredient, known for its longevity and collagen stimulation. However, the key differences lie in comfort and patient experience.

Similarities

• Safe, naturally biodegradable CaHA base
• Targets facial lifting and skin rejuvenation
• Longer-lasting than HA-based fillers
• Stimulates collagen with gradual enhancement

Differences

• Lidocaine-infused formula in Radiesse Plus significantly reduces pain during injection
• Easier application for physicians, allowing smoother, more precise injections
• Less bruising and swelling due to reduced need for additional anesthetics

Key Ingredient: Calcium Hydroxylapatite (CaHA)

• Biocompatible, structurally similar to human bone minerals
• Non-allergenic and naturally absorbed by the body
• Microspheres suspended in a gel carrier—provides immediate volume and long-term stimulation
• Supported by clinical studies confirming its efficacy in collagen induction and structural skin improvement

Plus Version Add-on: Lidocaine

• A local anesthetic blended into the formula for a more comfortable treatment experience

A Biostimulatory Filler

Radiesse Plus belongs to the “Biostimulator” class of fillers, unlike typical HA fillers that focus only on volume. Results continue to improve over 3–6 months, and effects may last beyond 12–18 months.

Why Radiesse Plus?

1. Volume + Lift + Collagen Stimulation
   • Immediate volume: CaHA gel provides instant fullness
   • Long-term skin rejuvenation: Stimulates collagen for tighter, more youthful skin
2. Long-lasting effects: 12–24 months
3. Natural-looking outcomes
   • Unlike HA fillers, Radiesse Plus doesn’t absorb water, avoiding puffiness
   • Blends seamlessly with facial contours
4. High safety profile
   • FDA-approved
   • Biodegradable and non-allergenic
   • Requires expert application for optimal results

Radiesse Plus vs HA (Comparison)

Can they be used together?

Yes. For example:

• HA for delicate areas like under-eyes
• Radiesse Plus for jawline or cheeks

Best Injection Areas for Radiesse Plus

Facial Areas

• Nasolabial folds: Reduces deep lines and lifts mid-face
• Chin augmentation: Adds natural projection without swelling
• Hollow temples: Restores volume and facial harmony
• Jawline contouring: Defines and lifts sagging cheeks

Body Areas

• Hands: Rejuvenates thinning skin with visible veins
• Neck: Tightens sagging skin non-surgically
• Upper arms, thighs, knees: Firms loose or uneven skin

Unsuitable Areas

• Under-eyes: Risk of lumpiness or “bulging” due to thick formula
• Lips: May feel stiff, unnatural
• Nose tip/bridge: Higher vascular risk
• Forehead: Risk of lumpiness or uneven texture

Who is Radiesse Plus Best For?

• Individuals with sagging skin, unclear jawlines, short chins, or deep nasolabial folds
• Those with thinning skin from age or frequent laser treatments
• People wanting longer-lasting results than HA fillers
• Individuals who found HA ineffective or short-lived
• Anyone seeking non-surgical facial rejuvenation

Who Should Avoid It?

• Very thin skin (e.g., under-eyes, lips)
• Allergies to Calcium or Lidocaine
• Pregnant or breastfeeding women
• Autoimmune or connective tissue disorder patients

Radiesse Plus Treats the Following:

1. Non-surgical facial lifting
2. Durable volume enhancement (nasolabial folds, chin, temples)
3. Collagen & elastin stimulation
4. Rejuvenation of hands and body areas
5. Structural restoration of aging or damaged skin

Injection Process

1. Consultation & planning – analyze sagging, volume loss, desired enhancements
2. Before photos – for result comparison
3. Injection – with needle or blunt cannula, ~30–45 minutes
4. Post-treatment evaluation – initial swelling is normal, collagen effects emerge in 1–3 months

What to Expect During Injection

Thanks to built-in Lidocaine, patients feel only mild pressure or warmth. This makes for a smoother, more comfortable experience.

Aftercare Instructions

First 24–48 Hours

• Apply cold compress if swollen
• Stay hydrated
• Avoid touching or pressing treated areas
• No intense workouts, alcohol, or spicy foods
• Contact your doctor if abnormal pain or redness occurs

Days 3–7

• Swelling subsides
• Avoid self-massage
• Bruising (if any) fades within 7–10 days

Pricing

Approx. cost:

• 34,990 THB per 1 box
• 59,900 THB per 2 box

Price Factors:

• Volume used
• Injection technique (e.g., blunt cannula vs. sharp needle)
• Physician expertise
• Additional procedures (e.g., HIFU (Ultraformer III), Ultherapy)
• Clinic promotions and post-care programs

Is Radiesse Plus Safe?

Yes, when performed by trained professionals. It’s FDA-approved since 2006 and widely used globally by dermatologists and aesthetic surgeons.

Safety Reasons

• CaHA is biocompatible
• Built-in Lidocaine reduces allergic reactions
• Doesn’t absorb water—low risk of puffiness
• No fibrosis or lumps if injected correctly

Risks if Misused

• Inexperienced injectors
• Fake products
• Incorrect anatomical locations (under-eyes, lips)

Side Effects

Common

• Mild swelling (1–3 days)
• Bruising (especially near blood vessels)
• Tightness or firmness (subsides in 1–2 weeks)

Rare (but be careful)

• Lumps from improper technique
• Allergic reactions
• Vascular occlusion (requires urgent care)

How Soon Will You See Results?

1. Immediate Effect

• Fuller features and smoother lines right after injection
• Mild swelling may occur but settles in a few days

2. Long-Term Collagen Boost

• New collagen production begins in 1–3 months
• Skin appears firmer and more youthful over time

3. Durability

• Typically lasts 12–24 months
• Even after the filler dissolves, collagen continues to benefit skin structure

Clinical studies show a 42% increase in collagen types I and III within 90 days

How to Spot Authentic Radiesse Plus

• Clearly labeled with Serial Number & Lot Number
• Box must say “Radiesse® Plus with Lidocaine”
• Packaging must be intact and sealed
• Certified distributors only—clinics should show official documentation
• Ask to open the box in front of you for assurance

Conclusion

Radiesse Plus is more than a filler—it’s a long-term collagen-stimulating treatment for lifting and rejuvenating aging or sagging skin. Results are both immediate and progressive, with effects lasting up to 1–2 years. Safe when administered by experts and proven to support natural skin restoration, Radiesse Plus offers a powerful option for non-surgical facial contouring. Always insist on authentic products and certified physicians for the best results.