Neuramis Filler Is It Good & Where to Inject?

Neuramis Filler has become one of the most popular Korean fillers in 2025, known for its smooth, natural texture and verified safety under Thai FDA approval. It’s designed for those who want subtle facial enhancement without surgery.

Developed by Medytox, the same company behind the renowned “Neuronox” Botox, Neuramis features SHAPE™ Technology, which enhances filler stability and ensures even, natural distribution under the skin.

Offering both quality and affordability, Neuramis is widely used in professional aesthetic clinics. It’s ideal for patients seeking a youthful, refreshed look that feels natural — with the flexibility to dissolve if adjustments are needed.

If you’ve ever wondered, “Is Neuramis good? Where can it be injected? And is it right for me?” This in-depth review from Smooth Clinic covers everything you need to know — brand insights, real patient experiences, and expert medical perspectives — so you can make the right choice confidently and safely.

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Neuramis Filler: Origin and Manufacture

Origin and Manufacturer

Neuramis Filler is a hyaluronic acid (HA) dermal filler from South Korea, developed by Medytox, the same pharmaceutical company behind the well-known Neuronox Botox. Medytox is recognized globally for its innovation and medical-grade manufacturing standards.

SHAPE™ Technology

Neuramis is formulated using SHAPE™ Technology (Stabilized Hyaluronic Acid and Purification Enhancement) — a proprietary process that stabilizes HA molecules and enhances gel purity. This creates a soft, smooth filler texture that maintains its shape and blends naturally with facial contours.

Safety and Certifications

The product is TFDA-approved (Thai FDA) and produced under strict GMP and ISO standards. It is specifically developed to suit Asian skin structures, offering both safety and natural-looking results.

Why Neuramis Is Popular

With its soft, flexible gel and natural finish, Neuramis has become one of the most trusted Korean fillers in Asia. It’s especially favored among patients seeking a youthful, balanced look without stiffness — combining high quality with affordability.

Key Features of Neuramis Filler

Soft and Natural-Looking Gel Texture

Neuramis Filler is formulated with an ultra-smooth gel that spreads evenly under the skin, creating a natural result without lumps or stiffness. It adapts well to facial movement for a soft, realistic finish.

SHAPE™ Technology for Enhanced Stability

Developed with SHAPE™ Technology (Stabilized Hyaluronic Acid and Purification Enhancement), Neuramis offers improved HA stability and gel uniformity — reducing the chance of swelling and ensuring longer-lasting results.

Certified Safety and Clinical Approval

Every Neuramis product is TFDA-approved (Thai FDA) and manufactured under GMP and ISO standards, ensuring high safety and clinical reliability in professional medical use.

Lidocaine for Added Comfort

Variants containing Lidocaine help minimize pain during injection, allowing for a smoother, more comfortable treatment experience.

Ideal for Asian Skin and Natural Results

The soft, flexible texture of Neuramis makes it ideal for Asian facial contours, blending seamlessly with natural features to achieve a youthful, balanced, and non-artificial look.

Neuramis Filler Variants and Differences

Overview of Neuramis Filler Line

The Neuramis filler range includes four main variants. Each is formulated with a specific gel density to suit different facial areas and treatment needs, all using the proprietary SHAPE™ Technology for enhanced stability and softness.

Neuramis Light – For Under-Eye and Fine Lines

Neuramis Light features an ultra-soft gel ideal for delicate skin areas such as under the eyes and tear troughs. It smooths out fine lines and brightens the under-eye area without puffiness.

Neuramis Deep – For Nasolabial Folds and Chin

Neuramis Deep has a medium gel consistency, designed to fill moderate wrinkles like nasolabial folds, chin lines, and marionette lines — offering a natural lift with a smooth finish.

Neuramis Volume – For Temples and Facial Contour

Neuramis Volume is the firmest formulation, perfect for deeper injections in areas like temples, cheeks, and chin. It helps restore lost volume and enhance facial contour with long-lasting structure.

Neuramis Lidocaine – For Comfortable Injection

Neuramis Lidocaine contains lidocaine for pain relief during injection, providing comfort without compromising gel performance or longevity.

Comparison Table: Neuramis Filler Variants

Variant Gel Density Recommended Areas Longevity (Approx.) Highlight
Neuramis Light Very soft Under eyes, tear troughs 6–9 months Natural and smooth finish
Neuramis Deep Medium Nasolabial folds, chin 9–12 months Smooths moderate wrinkles
Neuramis Volume Firm Temples, cheeks, chin Up to 12+ months Adds volume and contour
Neuramis Lidocaine Same as variant All areas (with lidocaine) Same as base type Comfort-enhancing injection

Where Can Neuramis Filler Be Injected?

Under Eyes – Brighten and Smooth the Eye Area

Neuramis Light is ideal for under-eye treatment, helping reduce dark circles and fine lines while maintaining a smooth, natural appearance without puffiness.

Nasolabial Folds – Soften Deep Smile Lines

Neuramis Deep effectively fills nasolabial folds and marionette lines, restoring volume and creating a youthful, lifted look around the mouth.

Chin – Define and Balance the Lower Face

Using Neuramis Deep or Volume, fillers in the chin area improve facial proportion, create a V-shaped contour, and enhance profile harmony.

Temples – Restore Volume and Facial Balance

Neuramis Volume replenishes hollow temples, softens harsh angles, and provides a fuller, more youthful facial outline.

Marionette Lines – Smooth Wrinkles Beside the Mouth

Injecting Neuramis Deep helps minimize marionette lines and drooping mouth corners, giving the face a softer and fresher appearance.

Quick Reference Table

Area Suitable Neuramis Variant Expected Result Gel Density
Under Eyes Neuramis Light Smooth, bright under-eye area Very soft
Nasolabial Folds Neuramis Deep Softer, lifted midface Medium
Chin Deep / Volume Sharper, more defined chin Medium–Firm
Temples Volume Fuller temples, balanced contour Firm
Marionette Lines Deep Reduced wrinkles, lifted corners Medium

How Long Does Neuramis Filler Last?

Neuramis fillers typically last between 9–12 months, depending on the product type and injection area. Lighter formulations such as Neuramis Light last around 6–9 months, while denser ones like Neuramis Volume can last over a year.

Factors That Affect Longevity

The filler’s longevity varies based on:

  • Treatment area (high-motion areas dissolve faster)
  • Amount injected and depth of placement
  • Aftercare habits, such as avoiding heat and facial massage
  • Metabolism rate — faster metabolism may shorten filler duration

Role of Injection Technique

Injection skill significantly impacts filler longevity. Experienced doctors who select the right filler type and injection depth help achieve smoother, longer-lasting results without migration or lumpiness.

Duration by Variant

  • Neuramis Light: 6–9 months
  • Neuramis Deep: 9–12 months
  • Neuramis Volume: 12+ months

The difference in longevity comes from the degree of HA cross-linking, which influences gel firmness and resistance to enzymatic breakdown.

How to Identify Authentic Neuramis Filler

Check the Import Label and Thai FDA Sticker

Authentic Neuramis fillers always include a Thai-language label with importer details and a valid Thai FDA license number. Missing labels or unclear print can indicate counterfeit products.

Verify with the QR Code on the Box

Each Neuramis box contains a QR code for authenticity verification. Scanning it should lead to Medytox’s official verification system, showing batch number and import status. If the link or data looks suspicious, avoid using it.

Examine the Packaging

Genuine packaging features crisp printing, consistent colors, and security holograms. Syringes are vacuum-sealed, with batch numbers matching the outer box and no leaks or discoloration.

Get Treated at Licensed Clinics Only

Always get injections at authorized aesthetic clinics using certified products. Reputable clinics, like Smooth Clinic, only use 100% genuine Neuramis fillers imported through official distributors and approved by the Thai FDA.

Neuramis vs Juvederm / Restylane / e.p.t.q.

Origin and Manufacturer

  • Neuramis: South Korea – Medytox
  • Juvederm: USA – Allergan
  • Restylane: Sweden – Galderma
  • e.p.t.q.: South Korea – Jetema

All are TFDA-approved fillers with different technologies and textures designed for various treatment needs.

Technology and Texture

  • Neuramis: SHAPE™ Technology for soft, stable texture
  • Juvederm: VYCROSS™ Technology for elasticity and lift
  • Restylane: NASHA™/OBT™ for firm structure and definition
  • e.p.t.q.: 9-Step Purification for high purity and smooth consistency

Longevity and Results

  • Neuramis: 9–12 months
  • Juvederm: 12–18 months
  • Restylane: 10–12 months
  • e.p.t.q.: 9–12 months

Pricing Overview (Approximate per 1 cc)

  • Neuramis: ฿7,000–9,000
  • Juvederm: ฿13,000–18,000
  • Restylane: ฿12,000–15,000
  • e.p.t.q.: ฿9,000–11,000

Neuramis offers a natural look with great value, while Juvederm and Restylane are preferred for longer-lasting structural results.

Comparison Table: Popular Filler Brands (That’s not the price at the clinic.)

Brand Country of Origin Technology Gel Texture Longevity Approx. Price Range (per 1 cc) Key Highlight
Neuramis South Korea SHAPE™ Soft, smooth 9–12 months 7,000–9,000 THB Natural results, great value, ideal for Asian skin
Juvederm United States VYCROSS™ Smooth, highly elastic 12–18 months 13,000–18,000 THB Excellent lifting and long-lasting structure
Restylane Sweden NASHA™ / OBT™ Firm, flexible 10–12 months 12,000–15,000 THB Effectively fills deep wrinkles and folds
e.p.t.q. South Korea 9-Step Purification Silky, refined 9–12 months 9,000–11,000 THB Safe, smooth texture, natural finish

Who Is Neuramis Filler Suitable For?

Ideal Candidates for Neuramis Filler

Neuramis Filler is ideal for those seeking natural facial enhancement without surgery, such as:

  • Individuals with hollow under-eyes, nasolabial folds, or sunken temples
  • Those who want to refine their chin contour or restore facial fullness
  • People who prefer soft, natural results suited to Asian facial features
  • First-time filler patients looking for safety and affordability

Its soft and flexible texture makes Neuramis perfect for achieving subtle improvements without altering one’s original facial identity.

Who Should Consult a Doctor First

Although Neuramis is a dissolvable HA filler, consultation is necessary in cases such as:

  • History of allergy to hyaluronic acid
  • Previous injections with permanent fillers
  • Skin infection or inflammation near the treatment area
  • Pregnancy or breastfeeding

A professional consultation ensures proper filler selection, dosage, and placement for safe, natural-looking results.

Doctor’s Recommendation

Medical professionals emphasize choosing licensed clinics using TFDA-approved products administered by trained physicians. Clinics like Smooth Clinic focus on natural balance and individualized treatment to ensure safety and aesthetic harmony.

Is Neuramis Filler Safe? Are There Any Side Effects?

Safety Profile of Neuramis Filler

Neuramis filler is made from hyaluronic acid (HA) — a biocompatible substance naturally found in the skin. It’s fully biodegradable and approved by the Thai FDA (TFDA), ensuring safety when administered by certified medical professionals.

Common Temporary Reactions

Mild, short-term reactions may occur after injection, such as:

  • Slight redness or swelling at the injection site
  • Minor bruising or tenderness for 1–3 days
  • Small needle marks that subside within a few days

These symptoms are normal and temporary, usually resolving on their own without medical intervention.

Rare Complications (Preventable)

Serious complications are rare but may occur if injected by unqualified providers or with counterfeit products, such as:

  • Lumps or filler migration
  • Infection due to poor hygiene
  • Vascular occlusion from incorrect injection depth

These risks can be prevented by visiting licensed clinics and getting treated by trained aesthetic doctors using authentic Neuramis fillers.

Can Neuramis Filler Be Dissolved If You Don’t Like the Result?

Neuramis Is a Dissolvable HA-Based Filler

Neuramis filler is made from hyaluronic acid (HA) — a type of filler that can be safely dissolved if the patient is dissatisfied with the result or experiences minor complications, such as unevenness or migration.

Dissolving with Hyaluronidase Enzyme

The enzyme Hyaluronidase breaks down hyaluronic acid molecules, allowing them to be naturally absorbed by the body. The dissolving effect starts within 24–48 hours, and the filler typically subsides completely within a few days.

Doctors carefully adjust the enzyme dosage to target only the treated area, avoiding over-dissolution or damage to surrounding tissues.

Procedure & Safety Precautions

  • Always get filler dissolving done by a licensed aesthetic doctor.
  • Never attempt self-injection — improper use can cause allergic reactions or skin necrosis.
  • Wait 1–2 weeks before re-injecting filler to let the skin recover properly.

Summary Before Deciding on Neuramis Filler

Why Neuramis Stands Out

Neuramis filler is among the most trusted Korean HA fillers, known for its smooth texture, stability, and natural-looking results. Its SHAPE™ Technology ensures even distribution under the skin and minimizes post-treatment inflammation.

Key Considerations Before Injection

While Neuramis is safe and dissolvable, patients should:

  • Get treated only by qualified filler specialists
  • Choose clinics using TFDA-approved authentic products
  • Avoid unlicensed providers or unverified filler sources

Consultation with an experienced doctor helps determine the right Neuramis variant for each area — Light for under-eyes, Deep for smile lines, or Volume for chin and temples.

Perfect for Natural Enhancements

Neuramis is ideal for individuals seeking subtle rejuvenation — fresher, softer, more youthful — without overcorrection. It suits both first-time patients and those switching from other brands for a gentler, natural result.

Frequently Asked Questions about Neuramis Filler

How long does Neuramis last?

Neuramis filler typically lasts around 9–12 months, depending on the variant and injection area. The Light version lasts 6–9 months, while the Volume version may last over a year with proper care.

Does Neuramis injection hurt?

Most Neuramis variants contain Lidocaine, a numbing agent that minimizes discomfort. With precise injection techniques, patients usually feel only mild pressure during treatment.

Is there any downtime after Neuramis filler?

No downtime is required. You can resume normal activities right after the procedure. Mild swelling or redness may occur for 1–2 days and typically subsides naturally.

How to check if Neuramis filler is genuine?

Genuine products have a Thai-language label, TFDA sticker, and QR code showing importer details. Always ask your doctor to open the box in front of you before injection.

Can Neuramis be dissolved if I don’t like the result?

Yes. Since Neuramis is a hyaluronic acid (HA) filler, it can be safely dissolved using Hyaluronidase enzyme under the supervision of a certified doctor.

References

  1. Neuramis — Medytox
  2. Thailand FDA – HA Dermal Filler
  3. The Smart Choice of HA Dermal Filler
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